Intestinal enterokinase deficiency. A newly-recognized disorder of protein digestion.
作者信息
Tarlow M J, Hadorn B, Arthurton M W, Lloyd J K
出版信息
Arch Dis Child. 1970 Oct;45(243):651-5. doi: 10.1136/adc.45.243.651.
Abstract
Enterokinase is an intestinal enzyme necessary for the activation of pancreatic proteolytic zymogens. Two children with absence of enterokinase activity in the duodenal juice and intestinal mucosa are described. Both had diarrhoea from birth and failed to thrive; one developed hypoproteinaemic oedema. Oral administration of pancreatic extract resulted in prompt control of symptoms and acceleration of growth. A simple screening test for enterokinase deficiency is described.
摘要
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