Fevre M, Boyar R M, Rollag M D
Ann Endocrinol (Paris). 1979;40(6):555-6.
Plasma melatonin and LH were measured at 20 minute intervals for 24 hours in four normal pubertal boys. All four subjects showed a significant augmentation of LH and melatonin during noctural sleep. There was also a significant correlation between the LH and melatonin levels (p less than 0.001). There were periods of episodic secretion of melanin during the diurnal waking period which seemed related to "stress". These data indicate that the peripheral concentrations of melatonin which occur during sleep are insufficient to prevent spontaneous LH secretion during puberty.
对四名正常青春期男孩在24小时内每隔20分钟测量一次血浆褪黑素和促黄体生成素(LH)。所有四名受试者在夜间睡眠期间促黄体生成素和褪黑素均显著增加。促黄体生成素水平与褪黑素水平之间也存在显著相关性(p<0.001)。在白天清醒期有间歇性褪黑素分泌期,这似乎与“应激”有关。这些数据表明,睡眠期间出现的外周褪黑素浓度不足以在青春期阻止促黄体生成素的自发分泌。