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结节病的克维姆试验。

The Kveim test in sarcoidosis.

作者信息

Mikhail J R, Mitchell D N

出版信息

Postgrad Med J. 1970 Aug;46(538):484-5. doi: 10.1136/pgmj.46.538.484.

Abstract

The Kveim test with a validated test-suspension was found to give an overall 71·9% positive result. A very high figure was obtained among patients with hilar or paratracheal gland involvement. Despite our enumeration of the difficulties and drawbacks inherent in Kveim testing, we find that this is a valuable test, providing one is aware of the pitfalls. Despite the finding of positive tests in conditions other than sarcoidosis, these are unlikely in practice to present a clinical problem in the differential diagnosis of suspected sarcoidosis. A microscopically positive test, therefore, remains clinically valuable. The test is also of very considerable importance in the clinical research into aetiology and pathogenesis of sarcoidosis.

摘要

使用经过验证的试验悬液进行的克维姆试验结果显示,总体阳性率为71.9%。在肺门或气管旁淋巴结受累的患者中得到了非常高的阳性率。尽管我们列举了克维姆试验固有的困难和缺点,但我们发现,如果了解其中的陷阱,这仍是一项有价值的试验。尽管在结节病以外的疾病中也发现了阳性试验结果,但在实际中这些不太可能在疑似结节病的鉴别诊断中造成临床问题。因此,显微镜下呈阳性的试验在临床上仍然具有价值。该试验在结节病病因和发病机制的临床研究中也非常重要。

引用本文的文献

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Diagnostic yield of the Kveim test in sarcoidosis patients.结节病患者中Kveim试验的诊断率
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2
Is micropapular sarcoidosis tuberculosis?微丘疹型结节病是结核病吗?
J R Soc Med. 1981 Feb;74(2):140-4. doi: 10.1177/014107688107400210.
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Sarcoidosis and Crohn's disease.结节病和克罗恩病。
Proc R Soc Med. 1971 Sep;64(9):944-6. doi: 10.1177/003591577106400930.

本文引用的文献

2
The preparation and standardization of Kveim testing antigen.
Am Rev Respir Dis. 1961 Nov;84(5)Pt 2:86-8. doi: 10.1164/arrd.1961.84.5P2.86.
3
The Nickerson-Kveim reaction in sarcoidosis.结节病中的尼克森-克维姆反应。
Am J Med. 1954 Jun;16(6):790-803. doi: 10.1016/0002-9343(54)90443-x.
4
The Kveim test in Crohn's disease.
Lancet. 1969 Sep 13;2(7620):571-3. doi: 10.1016/s0140-6736(69)90265-7.

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