结节病中的Kveim诱发巨噬细胞移动抑制因子（Kmif）试验
The Kmif (Kveim-induced macrophage migration inhibition factor) test in sarcoidosis.
作者信息
Williams W J, Pioli E, Jones D J, Dighero M
出版信息
J Clin Pathol. 1972 Nov;25(11):951-4. doi: 10.1136/jcp.25.11.951.
Abstract
Circulating lymphocytes from 30 patients with sarcoidosis when stimulated in vitro with Kveim-induced macrophage migration factor, the Kmif test, produced a guinea-pig macrophage migration inhibition factor in 21 of 30 cases (70%). In those patients not on steroids the results showed a good correlation with the cutaneous Kveim test. One positive test was found in 16 normal subjects. Our results suggest that the Kmif test may prove a useful rapid alternative to the Kveim test.
摘要
用克维姆诱导的巨噬细胞游走因子（Kmif试验）在体外刺激30例结节病患者的循环淋巴细胞时，30例中有21例（70%）产生了豚鼠巨噬细胞游走抑制因子。在未使用类固醇的患者中，结果与皮肤克维姆试验显示出良好的相关性。16名正常受试者中有1例试验呈阳性。我们的结果表明，Kmif试验可能是一种有用的、可替代克维姆试验的快速方法。
相似文献
1
The Kmif (Kveim-induced macrophage migration inhibition factor) test in sarcoidosis.结节病中的Kveim诱发巨噬细胞移动抑制因子（Kmif）试验
J Clin Pathol. 1972 Nov;25(11):951-4. doi: 10.1136/jcp.25.11.951.
2
In vitro Kveim (KMIF) test.体外克维姆（KMIF）试验。
Z Erkr Atmungsorgane. 1977 Aug;149(2):226-30.
3
Comparative in vitro reactivities of leukocytes from sarcoids and normals to different Kveim preparations.类肉瘤患者和正常人白细胞对不同克维姆制剂的体外反应性比较
Ann N Y Acad Sci. 1976;278:700-10. doi: 10.1111/j.1749-6632.1976.tb47084.x.
4
In vitro study of macrophages from patients with sarcoidosis.结节病患者巨噬细胞的体外研究。
Can Med Assoc J. 1972 Sep 23;107(6):509-15.
5
[Leukocyte migration inhibition test using diluted Kveim antigen in the diagnosis of sarcoidosis].
Pol Tyg Lek. 1977 Oct 24;32(43):1677-9.
6
[The leukocyte migration inhibition test with Kveim antigen in sarcoidosis].
Boll Soc Ital Biol Sper. 1973 Mar 15;49(5):318-23.
7
Leukocyte migration agarose test (LMAT) in sarcoidosis using Kveim test material.使用克维姆试验材料的结节病白细胞迁移琼脂糖试验（LMAT）
Br J Dermatol. 1978 Sep;99(3):263-70. doi: 10.1111/j.1365-2133.1978.tb01995.x.
8
[Kveim test performed with antigen obtained from lymph nodes].[用从淋巴结获取的抗原进行克维姆试验]
Med Cutan Ibero Lat Am. 1982;10(4):255-60.
9
A search for thymie (T) lymphocyte inhibitory factors in sarcoid sera.对结节病血清中胸腺（T）淋巴细胞抑制因子的研究。
Z Erkr Atmungsorgane. 1977 Aug;149(2):253-8.
10
Early cellular responses to intradermal injection of Kveim suspension in normal subjects and those with sarcoidosis.正常受试者和结节病患者对皮内注射克维姆悬液的早期细胞反应。
J Clin Pathol. 1986 Feb;39(2):176-82. doi: 10.1136/jcp.39.2.176.
引用本文的文献
1
Cellular immunity during follow-up of patients with sarcoidosis of varying duration.不同病程结节病患者随访期间的细胞免疫
Clin Exp Immunol. 1982 Oct;50(1):25-33.
2
Fine structure and histochemistry of epithelioid cells in sarcoidosis.结节病中上皮样细胞的精细结构与组织化学
Thorax. 1974 Jan;29(1):115-20. doi: 10.1136/thx.29.1.115.
3
Halothane macrophage migration inhibtiion factor test in halothane-associated hepatitis.氟烷相关性肝炎中的氟烷巨噬细胞移动抑制因子试验
J Clin Pathol. 1977 Apr;30(4):312-6. doi: 10.1136/jcp.30.4.312.
本文引用的文献
1
The preparation and standardization of Kveim testing antigen.克维姆试验抗原的制备与标准化
Am Rev Respir Dis. 1961 Nov;84(5)Pt 2:86-8. doi: 10.1164/arrd.1961.84.5P2.86.
2
Human lymphocyte migration as a parameter of hypersensitivity.人类淋巴细胞迁移作为超敏反应的一个参数。
Acta Med Scand. 1967 Feb;181(2):247-56. doi: 10.1111/j.0954-6820.1967.tb07255.x.
3
Sarcoidosis. An in vitro Kveim reaction based on the leucocyte migration test.
Acta Pathol Microbiol Scand. 1969;76(3):493-4. doi: 10.1111/j.1699-0463.1969.tb03279.x.
4
Effects of corticosteroid therapy on kveim reactivity in sarcoidosis.皮质类固醇疗法对结节病患者Kveim反应性的影响。
Am Rev Respir Dis. 1969 Apr;99(4):614-6. doi: 10.1164/arrd.1969.99.4P1.614.
5
Lymphocyte sensitization in sarcoidosis.结节病中的淋巴细胞致敏
Br Med J. 1971 Apr 17;2(5754):143-5. doi: 10.1136/bmj.2.5754.143.
6
In-vitro inhibition of leucocyte migration in Crohn's disease by a sarcoid spleen suspension.结节病脾脏悬液对克罗恩病白细胞迁移的体外抑制作用
Br Med J. 1971 Jul 17;3(5767):155-7. doi: 10.1136/bmj.3.5767.155.
7
8
Leucocyte migration inhibition with Kveim antigen in Crohn's disease.克罗恩病中Kveim抗原所致的白细胞游走抑制
Clin Exp Immunol. 1971 Dec;9(6):707-11.
9
A leucocyte migration technique for in vitro detection of cellular (delayed type) hypersensitivity in man.一种用于体外检测人体细胞（迟发型）超敏反应的白细胞迁移技术。
Dan Med Bull. 1969 Jan;16(1):1-6.
10
Syndrome of multiple osseous defects.多发性骨缺损综合征
Lancet. 1972 Jan 29;1(7744):260-1. doi: 10.1016/s0140-6736(72)90648-4.
Zotero 插件