结节病中的Kveim诱发巨噬细胞移动抑制因子（Kmif）试验
The Kmif (Kveim-induced macrophage migration inhibition factor) test in sarcoidosis.
作者信息
Williams W J, Pioli E, Jones D J, Dighero M
出版信息
J Clin Pathol. 1972 Nov;25(11):951-4. doi: 10.1136/jcp.25.11.951.
Abstract
Circulating lymphocytes from 30 patients with sarcoidosis when stimulated in vitro with Kveim-induced macrophage migration factor, the Kmif test, produced a guinea-pig macrophage migration inhibition factor in 21 of 30 cases (70%). In those patients not on steroids the results showed a good correlation with the cutaneous Kveim test. One positive test was found in 16 normal subjects. Our results suggest that the Kmif test may prove a useful rapid alternative to the Kveim test.
摘要
用克维姆诱导的巨噬细胞游走因子（Kmif试验）在体外刺激30例结节病患者的循环淋巴细胞时，30例中有21例（70%）产生了豚鼠巨噬细胞游走抑制因子。在未使用类固醇的患者中，结果与皮肤克维姆试验显示出良好的相关性。16名正常受试者中有1例试验呈阳性。我们的结果表明，Kmif试验可能是一种有用的、可替代克维姆试验的快速方法。
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