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与子宫肌瘤相关的子宫内膜变化。

Endometrial changes associated with myomata of the uterus.

作者信息

Deligdish L, Loewenthal M

出版信息

J Clin Pathol. 1970 Nov;23(8):676-80. doi: 10.1136/jcp.23.8.676.

DOI:10.1136/jcp.23.8.676
PMID:5488038
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC476867/
Abstract

The endometrium of 30 uteruses with myomata was studied at four standard sites. Glandular atrophy over a myoma or opposite a myoma was the most constant finding. At the margin of a myoma hyperplastic glands were frequently found, and distorted, elongated, or dilated glands were present at this site in half of all specimens. Other changes included adenomyosis and the separation of glands by muscle fibres from the basal layer of the endometrium. The coexistence of many of these findings in endometrial curettings can lead to the histological diagnosis of uterine myomata. Two factors, mechanical and hormonal, may be responsible and their mechanisms are discussed.

摘要

对30例患有肌瘤的子宫的子宫内膜在四个标准部位进行了研究。肌瘤上方或相对位置的腺体萎缩是最常见的发现。在肌瘤边缘经常发现增生性腺体,并且在所有标本的一半中,该部位存在扭曲、拉长或扩张的腺体。其他变化包括子宫腺肌病以及子宫内膜基底层的肌纤维将腺体分开。这些发现中的许多在子宫内膜刮除物中共存可导致子宫肌瘤的组织学诊断。可能有机械和激素两个因素起作用,并对其机制进行了讨论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8724/476867/e215964cf032/jclinpath00088-0031-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8724/476867/4922efceeaf8/jclinpath00088-0029-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8724/476867/95c3c21c6209/jclinpath00088-0029-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8724/476867/e866cbdbeaf0/jclinpath00088-0030-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8724/476867/58c9849b51de/jclinpath00088-0030-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8724/476867/d434816fa845/jclinpath00088-0030-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8724/476867/1d5f04279bc0/jclinpath00088-0031-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8724/476867/e215964cf032/jclinpath00088-0031-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8724/476867/4922efceeaf8/jclinpath00088-0029-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8724/476867/95c3c21c6209/jclinpath00088-0029-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8724/476867/e866cbdbeaf0/jclinpath00088-0030-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8724/476867/58c9849b51de/jclinpath00088-0030-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8724/476867/d434816fa845/jclinpath00088-0030-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8724/476867/1d5f04279bc0/jclinpath00088-0031-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8724/476867/e215964cf032/jclinpath00088-0031-b.jpg

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本文引用的文献

1
The mechanism of uterine bleeding in the presence of fibromyomas.子宫肌瘤存在时子宫出血的机制。
Am Surg. 1960 Jan;26:21-3.
2
[ON CHANGES IN THE UTERINE MUCOSA IN MYOMA].[论子宫肌瘤中子宫黏膜的变化]
Zentralbl Gynakol. 1964 Apr 4;86:471-3.
3
SUBMUCOUS MYOMAS.黏膜下肌瘤
Biomechanical Forces Determine Fibroid Stem Cell Transformation and the Receptivity Status of the Endometrium: A Critical Appraisal.
生物力学力决定了纤维瘤干细胞的转化和子宫内膜的接受状态:批判性评价。
Int J Mol Sci. 2022 Nov 17;23(22):14201. doi: 10.3390/ijms232214201.
4
Understanding the Impact of Uterine Fibroids on Human Endometrium Function.了解子宫肌瘤对人类子宫内膜功能的影响。
Front Cell Dev Biol. 2021 May 25;9:633180. doi: 10.3389/fcell.2021.633180. eCollection 2021.
5
Moving Toward Individualized Medicine for Uterine Leiomyomas.迈向子宫肌瘤个体化医学
Obstet Gynecol. 2018 Oct;132(4):961-971. doi: 10.1097/AOG.0000000000002785.
6
Myomas and Adenomyosis: Impact on Reproductive Outcome.子宫肌瘤和子宫腺肌病:对生殖结局的影响。
Biomed Res Int. 2017;2017:5926470. doi: 10.1155/2017/5926470. Epub 2017 Nov 6.
7
Ayurvedic Management of Recurrent Abortions due to Uterine Fibroid.子宫肌瘤所致复发性流产的阿育吠陀疗法
Anc Sci Life. 2017 Jan-Mar;36(3):159-162. doi: 10.4103/asl.ASL_189_15.
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The assessment of myometrium perfusion in patients with uterine fibroid by arterial spin labeling MRI.
Springerplus. 2016 Nov 3;5(1):1907. doi: 10.1186/s40064-016-3596-0. eCollection 2016.
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Uterine Leiomyomas: An ENIGMA.子宫平滑肌瘤:一个谜团。
J Midlife Health. 2016 Jan-Mar;7(1):22-7. doi: 10.4103/0976-7800.179170.
10
Laparoscopic myomectomy.腹腔镜子宫肌瘤切除术
J Med Life. 2014 Oct-Dec;7(4):522-4.
Acta Obstet Gynecol Scand. 1964;42:383-98. doi: 10.3109/00016346409158157.
4
[Contribution to the hormonal study of fibromas: determination of estrogens in the blood. Fibromas and uterine mucous membranes].[对纤维瘤激素研究的贡献:血液中雌激素的测定。纤维瘤与子宫黏膜]
Presse Med (1893). 1961 Nov 18;69:2191-3.