孕期菌尿症采用链霉素和磺胺甲氧嗪单剂量疗法。
Single-dose therapy with streptomycin and sulfametopyrazine for bacteriuria during pregnancy.
作者信息
Williams J D, Smith E K
出版信息
Br Med J. 1970 Dec 12;4(5736):651-3. doi: 10.1136/bmj.4.5736.651.
Abstract
One hundred and sixty-three patients with bacteriuria in pregnancy were treated with a single dose of antibiotic. Four regimens were used: sulfadoxine (sulphormethoxine) 2 g., sulfametopyrazine 2 g., streptomycin 1 g., and a combination of sulfametopyrazine 2 g. and streptomycin 1 g. The highest cure rate of 77% was achieved with streptomycin and sulfametopyrazine. The long-acting sulphonamides alone gave a cure rate of 55% while streptomycin alone eradicated 43% of the infections. Despite the high cure rate with combined therapy bacterial resistance developed in some cases.
摘要
163例孕期菌尿患者接受了单剂量抗生素治疗。采用了四种治疗方案：周效磺胺2克、磺胺甲氧嗪2克、链霉素1克，以及磺胺甲氧嗪2克与链霉素1克的联合用药。链霉素与磺胺甲氧嗪联合使用时治愈率最高，达77%。单独使用长效磺胺的治愈率为55%，而单独使用链霉素则清除了43%的感染病例。尽管联合治疗治愈率很高，但仍有一些病例出现了细菌耐药性。
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