Jedrychowski W, Adamczyk B, Jaskólka D
Rev Fr Mal Respir. 1979 Sep-Oct;7(5):471-4.
The main purpose of the paper was to find a possible relationship between smoking and immunological disorders, which are to be the common ground for chronic respiratory diseases. Measurements of IgG and IgA in saliva and blood serum were performed in 87 persons during medical check-up before admission to work in a sulphur mine. Persons with cough and/or sputum production usually in the morning or during the day or at night were defined as positive symptoms. From the study, different immunoglobulin patterns have emerged in saliva and serum in relation to smoking. IgG content in saliva of smokers was lower and IgA higher than in non-smokers. Levels of both immunoglobulins in serum were lower among smokers. In persons with respiratory symptoms IgG content in saliva was markedly lower especially in smokers.
该论文的主要目的是寻找吸烟与免疫紊乱之间可能存在的关系，而免疫紊乱是慢性呼吸道疾病的共同基础。在87名即将进入硫磺矿工作的人员入职前体检期间，对他们唾液和血清中的IgG和IgA进行了测量。通常在早晨、白天或晚上出现咳嗽和/或咳痰症状的人被定义为有阳性症状。从这项研究中可以看出，唾液和血清中与吸烟相关的免疫球蛋白模式有所不同。吸烟者唾液中的IgG含量低于非吸烟者，而IgA含量高于非吸烟者。吸烟者血清中这两种免疫球蛋白的水平都较低。有呼吸道症状的人唾液中的IgG含量明显较低，尤其是吸烟者。
