实验性变应性脑脊髓炎家兔脑脊液中β-葡萄糖醛酸酶活性
Cerebrospinal fluid beta-glucuronidase activity in rabbits with experimental allergic encephalomyelitis.
作者信息
Paterson P Y, Steele F M
出版信息
Clin Exp Immunol. 1970 Nov;7(5):759-68.
Abstract
Using a microassay, cerebrospinal fluid (CSF) β-glucuronidase activity increased precipitously in rabbits developing paralytic signs and characteristic lesions of experimental allergic encephalomyelitis (EAE). CSF protein concentration also increased in animals with EAE, but striking dissociation between protein and enzyme values in occasional rabbits suggests that each parameter represents an independent response to nervous tissue injury.
摘要
采用微量测定法，在出现麻痹症状和实验性变应性脑脊髓炎（EAE）特征性病变的家兔中，脑脊液（CSF）β-葡萄糖醛酸酶活性急剧增加。EAE动物的脑脊液蛋白浓度也升高，但偶尔有家兔的蛋白和酶值之间存在明显分离，这表明每个参数代表对神经组织损伤的独立反应。
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