Williams W J, Jenkins D, Erasmus D
Thorax. 1970 Nov;25(6):756-61. doi: 10.1136/thx.25.6.756.
A detailed study has been made of the ultrastructure of a cardiac myxoma from a man aged 41 years. It consists of abundant mucoid stroma in which are scattered single or grouped rounded or stellate cells. The stroma consists mainly of finely granular material with scanty fibrin which is seen predominantly on the surface aspect. No formed collagen is found. The myxoma cells contain numerous mitochondria, Golgi complexes and associated vesicles, moderate amounts of rough endoplasmic reticulum and scanty residual bodies. There is little evidence of pinocytosis. They also contain similar granular material to that found in the stroma. We consider, therefore, that the myxoma cells are biosynthetically active and are responsible for the production of the stroma. Morphologically the lesion does not show the features of a thrombus and we consider that it is most probably a neoplasm, although at present there is no evidence as to the cell of origin.
对一名41岁男性心脏黏液瘤的超微结构进行了详细研究。它由丰富的黏液样基质组成，其中散在单个或成群的圆形或星状细胞。基质主要由细颗粒物质组成，纤维蛋白较少，主要见于表面。未发现形成的胶原。黏液瘤细胞含有大量线粒体、高尔基体复合体及相关小泡、适量的粗面内质网和少量残余体。几乎没有胞饮作用的证据。它们还含有与基质中发现的类似颗粒物质。因此，我们认为黏液瘤细胞具有生物合成活性，负责基质的产生。从形态学上看，该病变不具有血栓的特征，我们认为它很可能是一种肿瘤，尽管目前尚无关于其起源细胞的证据。
