Twenty-one observations of cardiac myxomas (17 samples of operation material, 4 autopsies) were studied. Among them, 18 cases were located in the left atrium, 2 in the right atrium, 1 in the right ventricle. Macro- and microscopic characteristics of cardiac myxomas are presented. No signs of an organized thrombus were found. These studies confirm the current concept of cardiac myxoma as a neoplastic process.