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[Inhibition of cholinesterase activity in erythrocytes, ventricular muscle and brain of guinea pigs by subchronic and acute poisoning with diisopropylphosphofluoridate (DFP) and its reactivation of obidoxime].

作者信息

Ohnesorge F K

出版信息

Arch Toxikol. 1970;26(2):102-16.

PMID:5494768
Abstract
摘要

相似文献

1
[Inhibition of cholinesterase activity in erythrocytes, ventricular muscle and brain of guinea pigs by subchronic and acute poisoning with diisopropylphosphofluoridate (DFP) and its reactivation of obidoxime].[二异丙基氟磷酸酯（DFP）亚慢性和急性中毒对豚鼠红细胞、心室肌和脑胆碱酯酶活性的抑制作用及其与双复磷的重新激活作用]
Arch Toxikol. 1970;26(2):102-16.
2
Characterization of cholinesterases in various tissues of guinea pig with respect to their reactivation by obidoxime after inactivation by diisopropylfluorophosphate.用双异丙基氟磷酸酯使豚鼠各组织中的胆碱酯酶失活后，观察其被氯解磷定重新激活的情况，对各组织中的胆碱酯酶进行表征。
Arch Toxikol. 1972;29(3):235-45. doi: 10.1007/BF00315601.
3
In vivo reactivation by oximes of inhibited blood, brain and peripheral tissue cholinesterase activity following exposure to nerve agents in guinea pigs.在豚鼠体内，经神经毒剂暴露后，肟类化合物对血液、脑和周围组织胆碱酯酶活性的抑制作用的体内再激活。
Chem Biol Interact. 2010 Sep 6;187(1-3):207-14. doi: 10.1016/j.cbi.2010.03.006. Epub 2010 Mar 9.
4
[Trial of a new antidotal principle to experimental poisoning with DFP].[一种新型解毒原理用于二异丙基氟磷酸酯实验性中毒的试验]
Arch Toxikol. 1969;25(2):127-39.
5
Reactivation by pyridinium aldoxime methochloride (PAM) of inhibited cholinesterase activity in dogs after poisoning with pinacolyl methylphosphonofluoridate (soman).用氯解磷定（PAM）使犬中毒后被频那唑甲基磷酰氟（梭曼）抑制的胆碱酯酶活性重新激活。
J Pharmacol Exp Ther. 1967 May;156(2):345-51.
6
Effects of DFP and obidoxime on brain acetylcholine levels on brain and peripheral cholinesterases.二异丙基氟磷酸酯（DFP）和双复磷对脑乙酰胆碱水平以及脑和外周胆碱酯酶的影响。
Biochem Pharmacol. 1971 Nov;20(11):3029-37. doi: 10.1016/0006-2952(71)90107-9.
7
[On the capacity of obidoxime chloride to reactivate phosphorylated blood cholinesterases in vivo].[关于氯解磷定在体内重新激活磷酸化血液胆碱酯酶的能力]
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1968;260(2):130-1.
8
Biological responsiveness to cholinesterase inhibition: a test for exploring the developmental maturity of the cholinergic system.
J Neurosci Res. 1976;2(4):299-308. doi: 10.1002/jnr.490020407.
9
Strain differences in the laboratory rat: impact on the autonomic, behavioral, and biochemical response to cholinesterase inhibition.实验大鼠的品系差异：对胆碱酯酶抑制的自主神经、行为和生化反应的影响。
J Toxicol Environ Health. 1995 May;45(1):59-73. doi: 10.1080/15287399509531980.
10
[A new antidote principle for the treatment of alkylphosphate poisoning].
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1969;263(1):61-72.

引用本文的文献

1
Characterization of cholinesterases in various tissues of guinea pig with respect to their reactivation by obidoxime after inactivation by diisopropylfluorophosphate.用双异丙基氟磷酸酯使豚鼠各组织中的胆碱酯酶失活后，观察其被氯解磷定重新激活的情况，对各组织中的胆碱酯酶进行表征。
Arch Toxikol. 1972;29(3):235-45. doi: 10.1007/BF00315601.

本文引用的文献

1
Selective inhibition of pseudo-cholinesterase by diisopropyl fluorophosphonate.二异丙基氟磷酸酯对假性胆碱酯酶的选择性抑制作用。
Br J Pharmacol Chemother. 1947 Sep;2(3):173-80. doi: 10.1111/j.1476-5381.1947.tb00334.x.
2
Distribution of radiophosphorus in rabbit tissues after injection of phosphorus-labeled diisopropyl fluorophosphate.注射磷标记的氟磷酸二异丙酯后放射性磷在兔组织中的分布
J Pharmacol Exp Ther. 1950 Jan;98(1):77-84.
3
Labeling of red blood cells with radioactive diisopropylfluorophosphate (DFP32): evidence for an initial release of label.
用放射性二异丙基氟磷酸酯（DFP32）标记红细胞：标记物初始释放的证据。
J Lab Clin Med. 1960 Mar;55:416-24.
4
[COMPARATIVE STUDIES ON THE POSSIBILITY OF PENETRATION OF SOME ESTERASE-ACTIVATING OXIMES INTO THE CENTRAL NERVOUS SYSTEM].[某些酯酶激活肟类化合物穿透中枢神经系统可能性的比较研究]
Arzneimittelforschung. 1965 Feb;15:135-9.
5
[THE ANTIDOTE EFFECT OF BIS-(4-HYDROXYIMINOMETHYL-1-PYRIDINIUMMETHYL)-ETHER DICHLORIDE IN ALKYLPHOSPHATE-POISONED RATS].[二氯双（4-羟基亚胺甲基-1-吡啶甲基）醚对磷酸烷基酯中毒大鼠的解毒作用]
Arzneimittelforschung. 1964 Feb;14:85-8.
6
[PHARMACOLOGIC-TOXICOLOGIC STUDIES WITH THE DICHLORIDE OF BIS-(4-HYDROXYIMINOMETHYL-1-PYRIDINIUM-METHYL)-ETHER, A NEW ESTERASE REACTIVATOR].[双-(4-羟基亚胺甲基-1-吡啶鎓甲基)-醚二氯化物的药理毒理学研究，一种新型酯酶复活剂]
Arzneimittelforschung. 1964 Jan;14:5-11.
7
STUDIES ON THE MECHANISM OF ACQUIRED TOLERANCE BY RATS OF 0,0-DIETHYL S-2-(ETHYLTHIO)ETHYL PHOSPHORODITHIOATE (DI-SYSTON).0,0-二乙基-S-2-（乙硫基）乙基二硫代磷酸酯（敌杀磷）对大鼠获得性耐受性机制的研究
Arch Int Pharmacodyn Ther. 1964 Jun 1;149:560-70.
8
Red blood cell life span using DFP as a cohort label.以二异丙基氟磷酸酯（DFP）作为队列标签的红细胞寿命。
Blood. 1962 Jun;19:715-23.
9
The use of diisopropylfluorophosphate 32 for the determination of in-vivo red cell survival and plasma cholinesterase turnover rates.使用二异丙基氟磷酸酯32来测定体内红细胞存活率和血浆胆碱酯酶周转率。
J Lab Clin Med. 1958 Jun;51(6):916-25.
10
Toxicity and mechanism of action of di-syston.
AMA Arch Ind Health. 1958 Mar;17(3):192-9.