Komajda M, Beaufils H, Moulias R, Marescot M R, Drobinski G, Grosgogeat Y
Ann Med Interne (Paris). 1979;130(11):547-51.
The pathogenicity of primary non-obstructive myocardiopathies remains unknown at the present time. Immunological disturbances have been demonstrated but their role is open to discussion. A comparison between 37 such patients and 37 control subjects with cardiac insufficiency, similar according to age and sex, gave the following results: circulating immune complexes levels, anti-organ or anti-tissue antibody levels, and the levels of serum complement and its fractions were the same in both groups. Serum IgA levels were significantly higher in the "patient" group, and this appears to be partly related to alcoholism. Finally, an antimyocardial cellular immunity exists. These results would appear to demonstrate that conventional immunological techniques are of limited value in primary cardiac insufficiency.
原发性非梗阻性心肌病的致病性目前仍不清楚。免疫紊乱已得到证实，但其作用尚有待探讨。对37例此类患者与37例年龄和性别匹配的心力衰竭对照者进行比较，结果如下：两组的循环免疫复合物水平、抗器官或抗组织抗体水平以及血清补体及其各组分水平相同。“患者”组血清IgA水平显著更高，这似乎部分与酒精中毒有关。最后，存在抗心肌细胞免疫。这些结果似乎表明，传统免疫技术在原发性心力衰竭中的价值有限。
