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小肠结肠炎耶尔森菌菌株对化疗药物的敏感性

Sensitivity to chemotherapeutics of Yersinia enterocolitica strains.

作者信息

Zaremba M, Aldová E

出版信息

Arch Immunol Ther Exp (Warsz). 1979;27(6):847-52.

PMID:549534
Abstract

290 Y. enterocolitica strains were tested as regards their sensitivity to 20 chemotherapeutics. All the strains were isolated from fecal specimens taken from human beings in Czechoslovakia. It should be noted that the strains presented homologous group as they belonged to 3 serological group according to Winblad or IA according to Knapp and Thal, they also belonged to biotype 4 according to Nilehn. It has been found that apart from their homogenicity, they showed quite different patterns of sensitivity to chemotherapeutics. Among them quite a great number of the strains were of high level of resistance to antibiotics. It was not possible to transfer their resistance to the sensitive E. coli K12 strain. All the strains proved to produce betalactamase.

摘要

对290株小肠结肠炎耶尔森氏菌进行了对20种化疗药物敏感性的测试。所有菌株均从捷克斯洛伐克人类粪便标本中分离得到。应当指出的是,这些菌株呈现出同源群,因为根据温布拉德它们属于3个血清群,根据克纳普和塔尔属于IA血清群,根据尼勒恩它们也属于生物型4。已发现,除了它们的同质性外,它们对化疗药物的敏感性模式差异很大。其中相当多的菌株对抗生素具有高度抗性。无法将它们的抗性转移至敏感的大肠杆菌K12菌株。所有菌株均被证明可产生β-内酰胺酶。

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