Siddiqui M A, Mahmood I, Basit N, Ahmed S, Bukhari A Q
G Batteriol Virol Immunol. 1978 Jul-Dec;71(7-12):181-91.
Bactericidal, bacteriostatic, fungistatic and toxicological evaluaton of an emulsion containing 0.25% hexachlorophene (W/V), 9.5% terpineol (V/V), 1.5% oil of terpentine (V/V), 13% ethanol (V/V), 6% castor oil distillate 1201275 degrees C (V/V) and 6% sodium salt of the residue (W/V) in aqueous medium was performed. The bactericidal concentration for Salmonella typhi was found to be 1:400 which increased to 1:350 in the presence of 5% horse serum. The bacteriostatic concentration of the emulsion varied from organism to organism. A 4% solution of the emulsione was found to be most effective against Microsporum vanbreuseghemii showing an inhibition zone of 7.2 cm and was least effective on Aspergillus niger. 1 to 8% solution of the emulsion given orally or instilled into conjunctival sacs of albino mice indicated lethal and insignificant toxic manifestations respectively but a dose equivalent to 50 mg/Kg given subcutaneously was found to produce a subacute lethal effect in guinea pigs.
对一种乳液进行了杀菌、抑菌、抑真菌及毒理学评估，该乳液在水介质中含有0.25%（重量/体积）的六氯酚、9.5%（体积/体积）的松油醇、1.5%（体积/体积）的松节油、13%（体积/体积）的乙醇、6%（体积/体积）的蓖麻油馏出物120/127.5℃以及6%（重量/体积）的残渣钠盐。伤寒沙门氏菌的杀菌浓度为1:400，在5%马血清存在时增至1:350。该乳液的抑菌浓度因微生物种类而异。发现该乳液4%的溶液对范布利塞姆氏小孢子菌最有效，抑菌圈为7.2厘米，对黑曲霉最无效。经口给予或滴入白化小鼠结膜囊的1%至8%乳液溶液分别显示出致死和不明显的毒性表现，但皮下给予相当于50毫克/千克的剂量时，发现会在豚鼠中产生亚急性致死效应。
