Tomasi A M, Pirani R, Gruppillo P
G Ital Cardiol. 1979;9(12):1456-8.
In ten patients suffering from slight or moderate essential arterial hypertension, undergoing treatment with tienilic acid at 500 mg per day, various hemodynamic parameters were assessed by means of ecocardiographic and policardiographic studies carried out before, during and at the end of treatment. In all cases a return to normal blood pressure values was achieved. No statistically significant changes in these parameters were observed, whereas the blood tests showed a reduction in the uric acid level and a moderate reduction in the potassium level.
在10例患有轻度或中度原发性动脉高血压且每天接受500毫克替尼酸治疗的患者中,通过在治疗前、治疗期间和治疗结束时进行的超声心动图和多心图研究评估了各种血流动力学参数。在所有病例中,血压值均恢复正常。这些参数未观察到统计学上的显著变化,而血液检查显示尿酸水平降低,钾水平适度降低。