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滴滴涕模型底物二苯甲烷的细菌降解

Bacterial degradation of diphenylmethane, a DDT model substrate.

作者信息

Focht D D, Alexander M

出版信息

Appl Microbiol. 1970 Oct;20(4):608-11. doi: 10.1128/am.20.4.608-611.1970.

Abstract

A strain of Hydrogenomonas was isolated by elective culture in a solution with diphenylmethane, an analogue of DDT, as the sole carbon source. Constitutive enzymes effected the oxidation and fission of one of the benzene rings of diphenylmethane, and phenylacetic acid was found as a major degradation product. Small amounts of phenylglyoxylic and benzoic acids were also generated from diphenylmethane by the bacterium. Phenylacetic acid, which contains the second benzene ring of diphenylmethane, was metabolized by inducible enzymes.

摘要

通过在以二苯甲烷(一种滴滴涕类似物)作为唯一碳源的溶液中进行选择培养,分离出了一株氢单胞菌属菌株。组成酶催化二苯甲烷的一个苯环发生氧化和裂解,发现主要降解产物为苯乙酸。该细菌还从二苯甲烷中生成少量苯甲酰甲酸和苯甲酸。含有二苯甲烷第二个苯环的苯乙酸由诱导酶进行代谢。

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