Ambanelli U, Troise W, Fadda G, Nervetti A
Z Rheumatol. 1975 Nov-Dec;34(11-12):408-12.
The serum and synovial fluid concentrations of alpha2 macroglobulin and alpha2 neuramino glycoprotein of patients with rheumatoid arthritis have been studied. For, both protein fractions have antiprotease activity and inhibit, though to different degrees, many factors concerning inflammation. Even though both fractions have certain activities in common, in rheumatoid arthritis, we neither see a parallel increase nor antagonistic actions in the case of alpha2 macroglobulin and alpha2 neuramino-glycoprotein.
对类风湿性关节炎患者血清和滑液中α2巨球蛋白及α2神经氨酸糖蛋白的浓度进行了研究。因为这两种蛋白组分都具有抗蛋白酶活性,并且在不同程度上抑制许多与炎症相关的因子。尽管这两种组分有某些共同活性,但在类风湿性关节炎中,我们既未观察到α2巨球蛋白与α2神经氨酸糖蛋白呈平行升高,也未观察到它们的拮抗作用。