Davies R F, Major I R, Aberdeen E R
Br J Cancer. 1970 Dec;24(4):785-7. doi: 10.1038/bjc.1970.93.
Explants of lung from 1 month old inbred BALB/c mice were cultured in vitro for 4 days with 3-methylcholanthrene added to the culture medium at various dose levels. They were subsequently implanted subcutaneously into 6-week-old mice of the same strain.Lung adenomata appeared in a high proportion of explants.
将1月龄近交系BALB/c小鼠的肺外植体在含有不同剂量水平3-甲基胆蒽的培养基中体外培养4天。随后将它们皮下植入同品系6周龄小鼠体内。高比例的外植体出现了肺腺瘤。