化学致癌物诱导小鼠肺移植瘤中腺瘤的形成。
The induction of adenomata in mouse lung homografts by chemical carcinogens.
作者信息
Davies R F, Major I R, Aberdeen E R
出版信息
Br J Cancer. 1971 Sep;25(3):565-7. doi: 10.1038/bjc.1971.71.
Abstract
Implants of lung from 18-day-old embryo BALB/c mice of an inbred strain were exposed to 3,4-benz(a)pyrene or 1,2,5,6-dibenzanthracene and introduced subcutaneously into 6-week-old mice of the same strain. Lung adenomata developed within 16 weeks.There was no evidence of an effect of either chemical carcinogen on the subcutaneous tissue of the host animal.
摘要
将来自近交系18日龄胚胎BALB/c小鼠的肺植入物暴露于3,4-苯并(a)芘或1,2,5,6-二苯并蒽，然后皮下植入同品系6周龄小鼠体内。在16周内出现了肺腺瘤。没有证据表明这两种化学致癌物对宿主动物的皮下组织有影响。
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