一种用于区分镰状细胞性状和镰状细胞贫血的快速全血溶解度试验。
A rapid whole blood solubility test to differentiate the sickle-cell trait from sickle-cell anaemia.
作者信息
Huntsman R G, Barclay G P, Canning D M, Yawson G I
出版信息
J Clin Pathol. 1970 Dec;23(9):781-3. doi: 10.1136/jcp.23.9.781.
Abstract
A simple and rapid screening test which differentiates sickle-cell trait and sickle-cell anaemia is described. The test utilizes 0.1 ml of whole blood and is based on the low solubility of reduced sickle haemoglobin. Results intermediate between the sickle-cell trait and sickle-cell anaemia are obtained in unusual cases of sickle-cell anaemia with high foetal haemoglobin. The need to supplement the results with haematological and electrophoretic techniques is discusses.
摘要
本文描述了一种简单快速的筛查试验，可区分镰状细胞性状和镰状细胞贫血。该试验使用0.1毫升全血，基于还原型镰状血红蛋白的低溶解度。在胎儿血红蛋白含量高的镰状细胞贫血特殊病例中，会得到介于镰状细胞性状和镰状细胞贫血之间的结果。文中讨论了用血液学和电泳技术补充结果的必要性。
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A rapid whole blood solubility test to differentiate the sickle-cell trait from sickle-cell anaemia.一种用于区分镰状细胞性状和镰状细胞贫血的快速全血溶解度试验。
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