Serjeant G R, Richards R, Barbor P R, Milner P F
Br Med J. 1968 Jul 13;3(5610):86-91. doi: 10.1136/bmj.3.5610.86.
A study in Jamaica of 60 patients with sickle-cell anaemia over the age of 30 years showed that most of them were in full-time employment. Pains in the bones or joints, leg ulceration, and jaundice were the most frequent types of presentation, but only two patients had a haemoglobin level consistently below 6 g./ 100 ml. Most of the patients were well developed and of average height, and, though the development of secondary sexual characteristics was delayed, there was an average of 2.6 pregnancies per patient. These findings suggest that the course is more benign than has been realized.
在牙买加针对60名30岁以上镰状细胞贫血患者开展的一项研究表明，他们中的大多数人都有全职工作。骨骼或关节疼痛、腿部溃疡和黄疸是最常见的症状表现类型，但只有两名患者的血红蛋白水平持续低于6克/100毫升。大多数患者发育良好，身高处于平均水平，虽然第二性征发育延迟，但每位患者平均怀孕2.6次。这些研究结果表明，该疾病的病程比人们认识到的更为良性。
