Mendes E
Acta Allergol. 1975 Nov;30(5):267-71.
Bronchial secretion was tested by double gel-diffusion with sera from 100 asthmatic patients, 72 systemic lupus erythematosus patients, 29 patients with other diseases and 31 normal individuals. Positive gel-diffusion reactions were observed only in the sera from two patients with S.L.E. Sera from 100 asthmatic patients, 29 non-allergic patients and 31 normal individuals, tested with bronchial secretion by the passive haemagglutination and inhibition test, showed only three positive reactions with sera from asthmatic patients. Two problems were discussed: the immunological relationship between antigenic determinants found in the sputum and serum in S.L.E. patients; and the possibility that the bronchial secretion being reabsorbed might act as an auto-antigen.
采用双向凝胶扩散法，用100例哮喘患者、72例系统性红斑狼疮患者、29例其他疾病患者及31例正常人的血清检测支气管分泌物。仅在2例系统性红斑狼疮患者的血清中观察到阳性凝胶扩散反应。用支气管分泌物通过被动血凝和抑制试验检测100例哮喘患者、29例非过敏性患者及31例正常人的血清，仅在哮喘患者的血清中出现3例阳性反应。讨论了两个问题：系统性红斑狼疮患者痰液和血清中发现的抗原决定簇之间的免疫关系；以及支气管分泌物被重吸收后可能作为自身抗原的可能性。
