Meadows J C
J Neurol Neurosurg Psychiatry. 1970 Aug;33(4):519-23. doi: 10.1136/jnnp.33.4.519.
Muscle pain receptors have been studied in man. During the advance of an EMG needle pain is most regularly experienced as the muscle fascia is pierced. Further advancing the needle is usually quite painless. However, there are scantily distributed points within the muscle (pain spots') which may give rise to pain if encountered by the advancing needle. The nature of the responsible receptors is obscure but it is likely that pain may sometimes be caused by activation of nerve fibres (presumably from these receptors) coursing through the muscle rather than by activation of the receptors themselves. Intramuscular bleeding is unlikely to contribute often to the pain of needle electromyography. Mechanically sensitive pain spots' are more painful than other areas when stimulated electrically or injected with hypertonic (6%) saline. This suggests a common receptor. The high electrical threshold and relative invulnerability to pressure of afferent fibres from these receptors suggest that they are mainly of small diameter. These findings are discussed in relation to experimental work on pressure-pain receptors in animals.
人们已经对人体肌肉疼痛感受器进行了研究。在肌电图针推进过程中，当针刺穿肌肉筋膜时，最常感觉到疼痛。进一步推进针通常相当无痛。然而，肌肉内分布稀少的点（“疼痛点”）如果被推进的针碰到，可能会引起疼痛。引发疼痛的感受器的性质尚不清楚，但疼痛有时可能是由穿过肌肉的神经纤维（大概来自这些感受器）的激活引起的，而不是由感受器本身的激活引起的。肌内出血不太可能经常导致针电极肌电图检查时的疼痛。当用电刺激或注射高渗（6%）盐水时，机械敏感的“疼痛点”比其他区域更疼痛。这表明存在一种共同的感受器。这些感受器传入纤维的高电阈值和相对抗压性表明它们主要是小直径的。结合动物压力疼痛感受器的实验工作对这些发现进行了讨论。
