Mészáros M G, Guba F, Takács O
Acta Biol Acad Sci Hung. 1979;30(1):59-77.
Ultrastructural investigations were carried out parallel with biochemical measurements on the limb muscles of rabbits immobilized by putting in plaster. The cellular structure of normal and immobilized (1--6 weeks) m. soleus and m. gastrocnemius (red tonic and white tetanic, respectively) were compared. During immobilization significant changes occurred in the cellular structure of m. soleus, while little change was observed in the white fibres of m. gastrocnemius. The fibres of m. soleus decreased in diameter and fatty infiltration set in. The myofibrils decreased in amount and their structure was damaged and disorganized but did not disappear completely. Mitochondria showed little damage, like membraneous structures in general, in number. Loss of material seems to be by way of vesicles formed by the heavily invaginated plasma membrane and by the deflation of the numerous vesicles observed. The red fibres of m. gastrocnemius behaved like the fibres of m. soleus; in the white fibres some focal disorganization was observed near the Z line. The cystae of mitochondria and the SR appear to be dilated.
在对用石膏固定的家兔肢体肌肉进行生化测量的同时，进行了超微结构研究。比较了正常和固定（1 - 6周）的比目鱼肌和腓肠肌（分别为红色慢肌和白色快肌）的细胞结构。在固定期间，比目鱼肌的细胞结构发生了显著变化，而腓肠肌白色纤维的变化很小。比目鱼肌纤维直径减小，出现脂肪浸润。肌原纤维数量减少，其结构受损且紊乱，但并未完全消失。线粒体与一般膜性结构一样，损伤较小，数量未见明显减少。物质损失似乎是通过高度内陷的质膜形成的小泡以及观察到的大量小泡的萎缩来实现的。腓肠肌的红色纤维表现与比目鱼肌纤维相似；在白色纤维中，在Z线附近观察到一些局部紊乱。线粒体的囊泡和肌浆网似乎扩张。
