Hollósi G, Takács O, Guba F, Szöör A, Szilágyi T
Acta Biol Acad Sci Hung. 1977;28(2):205-12.
The effect of hypokinesis on the quantitative changes in the nucleic acids was studied in functionally different muscles of rabbits on the 5th, 10th, 14th and 28th days following plaster cast immobilization of the limbs. As a consequence of the immobilization, the total amount of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) decreased in both the tonic and the tetanic nuscles. The decrease was more marked in the tonic muscles. As a result of the hypokinesis, the RNA/DNA ratio increased in the m. gastrocnemius, and decreased in the m. soleus. The plaster cast immobilization has a greater effect on the homoeostasis of the nucleic acids of the tonic muscles than in the case of the tetanic muscles.
在兔肢体石膏固定后的第5天、第10天、第14天和第28天，研究了运动减少对功能不同肌肉中核酸定量变化的影响。由于固定，强直性和紧张性肌肉中的脱氧核糖核酸（DNA）和核糖核酸（RNA）总量均减少。强直性肌肉中的减少更为明显。由于运动减少，腓肠肌中的RNA/DNA比值升高，而比目鱼肌中的该比值降低。与紧张性肌肉相比，石膏固定对强直性肌肉核酸稳态的影响更大。
