Crews S, Ojala D, Posakony J, Nishiguchi J, Attardi G
Nature. 1979 Jan 18;277(5693):192-8. doi: 10.1038/277192a0.
A fragment of HeLa cell mitochondrial DNA containing the origin of replicaton has been sequenced. The precise position of the origin in this sequence has been identified by determining the nucleotide order in the 5'-end proximal portion of the heavy strand initiation fragment (7S DNA), and by aligning the two sequences.
一段包含复制起点的海拉细胞线粒体DNA片段已被测序。通过确定重链起始片段(7S DNA)5'-末端近端部分的核苷酸顺序,并将这两个序列进行比对,已确定了该序列中起点的精确位置。