马对破伤风类毒素的免疫反应。
The immune response of horses to tetanus toxoid.
作者信息
Jansen B C, Knoetze P C
出版信息
Onderstepoort J Vet Res. 1979 Dec;46(4):211-6.
An intramuscular injection of 8-16 Lf tetanus toxoid in water-in-oil emulsion protected adult horses against tetanus for at least 128 weeks. A booster dose of 8 Lf toxoid in aqueous solution protected them for a further period of at least 3 1/2 years. Colostral immunity protected foals for at least 10 weeks. An intramuscular injection of 8 Lf toxoid in water-in-oil emulsion given to foals from immune dams when they were 10-18 weeks old did not elicit any antibody response. They did respond, however, to a booster injection of 8 Lf toxoid in aqueous solution given 12 weeks after the first dose. New-born foals were shown to be inherently unable to respond to an injection of tetanus toxoid.
肌肉注射8 - 16个絮状单位（Lf）的破伤风类毒素油包水乳剂可使成年马预防破伤风至少128周。注射一剂8 Lf的水溶液类毒素加强针可使它们在至少3.5年的时间内持续得到保护。初乳免疫可使马驹获得至少10周的保护。给10 - 18周龄、来自免疫母马的马驹肌肉注射8 Lf油包水乳剂类毒素，未引发任何抗体反应。然而，在首剂注射12周后注射一剂8 Lf水溶液类毒素加强针，它们会产生反应。新生马驹被证明天生无法对破伤风类毒素注射产生反应。
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