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[对患有和未患有甲状腺肿的猪甲状腺进行组织计量学研究,特别提及形态学发现对评估甲状腺功能的重要性]

[Histometric studies of thyroid glands of swine with treated and untreated strumata with special reference to the importance of morphological findings for the assessment of thyroid function].

作者信息

Seffner W, Heller P

出版信息

Arch Exp Veterinarmed. 1979;33(6):861-7.

PMID:551750
Abstract

Thyreocyte measurements were applied to 20 thyroids each of three groups of pigs for slaughter kept in the region of the Baltic coast. The first group consisted of clinically intact animals, the second of animals with untreated goiters, and the third of animals with goiters and potassium-iodine treatment. Hundred cells were measured in each of the animals, the magnification factor being 2,000. Mean values were calculated for each animal and group. The mean epithelial levels were 7.34 +/- 0.71 micrometer in Group 1, 13.77 +/- 1.97 micrometer in Group 2, and 4.25 +/- 0.52 micrometer in Group 3. The follicles recorded from the third group were one-a-half to three times as large as those recorded from the first. The mean thyroid weights were 11.8 +/- 5.0 g in the first group, 46.3 +/- 28.9 g in the second, and 23.5 +/- 7.9 g in the third. The relevance of such morphological findings to assessment of thyroid function is discussed. It is proposed to include such tests in any assessment of a problem situation in the context of thyroid function and in any evaluation of therapeutic success.

摘要

对波罗的海沿岸地区饲养的三组用于屠宰的猪,每组20头甲状腺进行了甲状腺细胞测量。第一组由临床健康的动物组成,第二组由未经治疗的甲状腺肿动物组成,第三组由患有甲状腺肿并接受碘化钾治疗的动物组成。对每组动物中的100个细胞进行测量,放大倍数为2000倍。计算每只动物和每组的平均值。第一组的平均上皮细胞水平为7.34±0.71微米,第二组为13.77±1.97微米,第三组为4.25±0.52微米。第三组记录的滤泡大小是第一组的1.5到3倍。第一组的平均甲状腺重量为11.8±5.0克,第二组为46.3±28.9克,第三组为23.5±7.9克。讨论了这些形态学发现与甲状腺功能评估的相关性。建议在甲状腺功能问题情况的任何评估以及治疗成功的任何评估中纳入此类测试。

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