Jarosz J, Spiewak N
Cytobios. 1979;26(103-104):203-19.
Using an assay system for lysozyme activity determination in which haemolymph was compared in activity to known standards, the quantitative shifts in the lysozyme activity level of larvae and pupae of Galleria mellonella, after particulate and soluble materials injection, were compared. The level of this activity in all injected larvae was higher fro that of pupae, but the immune response of pupae was more effective in all treatments when compared with activity in the non-injected controls. Furthermore, there was a significant higher level of lysozyme activity in pupae subjected to mechanical immunizing agents, except inversed pupae in which alternation in activity was not significantly different from activity in the corresponding nonexposed insects. Although the exact role of lysozyme in insect immunity is still uncertain, it is possible that this lysosomal enzyme may degrade the cell wall of susceptible parasites prior to being phagocytosed, and thereby act as a nonspecific inducible humoral defence molecule.
利用一种溶菌酶活性测定分析系统，该系统将血淋巴的活性与已知标准进行比较，比较了注射颗粒物质和可溶性物质后，大蜡螟幼虫和蛹溶菌酶活性水平的定量变化。所有注射幼虫的这种活性水平高于蛹，但与未注射对照的活性相比，蛹在所有处理中的免疫反应更有效。此外，接受机械免疫剂处理的蛹中溶菌酶活性水平显著更高，除了倒置蛹，其活性变化与相应未暴露昆虫的活性没有显著差异。虽然溶菌酶在昆虫免疫中的确切作用仍不确定，但这种溶酶体酶有可能在被吞噬之前降解易感寄生虫的细胞壁，从而作为一种非特异性诱导性体液防御分子发挥作用。
