Jarosz J
Unit of Insect Pathology, Institute of Biology, Maria Curie-Skłodowska University, Lublin, Poland.
Cytobios. 1988;53(212):19-29.
In a series of induction experiments using various Ringer solutions attempts were made to determine whether saline W, a physiological salt solution for Lepidoptera, when injected into the larval haemocoel of the greater wax moth could be recognized by the insect as a non-self molecule. Laboratory bioassays indicated the loss of insect body integrity following intracoelomic injection of saline W and three other salines, increased levels of haemolymph lysozyme activity (EC 3. 2. 1. 17), and elevated resistance to the bacterial parasite, Pseudomonas aeruginosa. The inducing effect of saline W was stronger than dipterous Ringer's solution or other physiological salines. The stimulating effects indicate that the moth distinguishes between self and non-self, and this provides a new insight into the induction of the immune response.
在一系列使用各种林格氏液的诱导实验中，研究人员试图确定鳞翅目昆虫的生理盐溶液——W型生理盐水，注入大蜡螟幼虫血腔后，是否会被昆虫识别为非自身分子。实验室生物测定表明，向体腔内注射W型生理盐水和其他三种生理盐水后，昆虫身体完整性丧失，血淋巴溶菌酶活性（EC 3.2.1.17）水平升高，对细菌性寄生虫铜绿假单胞菌的抵抗力增强。W型生理盐水的诱导作用比双翅目林格氏液或其他生理盐溶液更强。这些刺激作用表明，大蜡螟能够区分自身和非自身，这为免疫反应的诱导提供了新的见解。
