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[5月4日和5日在亚琛举行的关于黏液溶解剂,尤其是口服乙酰半胱氨酸的国际研讨会结论]

[Conclusions of an international symposium held at Aachen on 4 and 5 May about mucolytic agents, especially oral acetylcysteine].

作者信息

Minette A

出版信息

Rev Inst Hyg Mines (Hasselt). 1979;34(3):150-6, 159-65.

PMID:552659
Abstract

The usefulness of mucolytics for clinical purposes remains controversial. Although many authors agree with the opinion that some of these drugs, above all aerosols of acetylcysteine at convenient dosages, provided they are associated with beta 2-sympathomimetics, may be useful in the treatment of bronchial obstruction due to inspissated mucus in excess in the lumens, many specialists remain reluctant concerning the activity of mucolytics given by mouth. It seemed therefore interesting to organize an international meeting on this topic. First of all, I would like to pay honour to the initiative of the Zambon Laboratories who organized this symposium. I would also like to express my gratitude for having been involved in the preparation of the programme of these days and having been asked to present the general conclusions of the meeting. The following pages are devoted to these conclusions. We shall repeatedly make reference to the works which were presented in extenso during the meeting. The general report of the symposium will shortly appear in a special supplement of the European Journal of Respiratory Diseases. It seems however useful to give at the end of our text the complete list of the presented lectures.

摘要

黏液溶解剂用于临床的有效性仍存在争议。尽管许多作者认同这样的观点,即某些此类药物,尤其是剂量适宜的乙酰半胱氨酸气雾剂,只要与β2 - 拟交感神经药联合使用,可能对治疗因管腔内黏液分泌过多浓稠而导致的支气管阻塞有用,但许多专家对口服黏液溶解剂的活性仍持保留态度。因此,组织一次关于这个主题的国际会议似乎很有意义。首先,我要赞扬赞邦实验室组织这次研讨会的倡议。我也要感谢参与这些天会议议程的准备工作,并受邀介绍会议的总体结论。以下几页将阐述这些结论。我们会多次提及会议期间详尽展示的研究成果。研讨会的总报告将很快发表在《欧洲呼吸疾病杂志》的一期特别增刊上。不过,在本文结尾列出所有讲座的完整清单似乎是有用的。

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