Williams J P, Hughes S M
Acta Anat (Basel). 1979;105(4):461-8. doi: 10.1159/000145153.
By following the development of individual mice from birth to 200 days of age, it was found that the skull of the homozygous mutant (dwdw) was 5% shorter than that of the normal phenotype at birth and some 30% shorter at 200 days of age. During post-natal growth of the skull, the cranium was least altered but the facial skeleton was greatly affected. The differences seen in different parts of the skull are attributed to the peak growth velocities of the various parts occurring at different times.
通过追踪个体小鼠从出生到200日龄的发育过程，发现纯合突变体（dwdw）的头骨在出生时比正常表型的头骨短5%，在200日龄时短约30%。在出生后头骨的生长过程中，颅骨变化最小，但面部骨骼受到很大影响。头骨不同部位出现的差异归因于各个部位在不同时间出现的生长速度峰值。
