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[百日咳血清学诊断的近期趋势]

[Recent trends in the serologic diagnosis of pertussis].

作者信息

Chiumello R, Lusco G, Garlaschi M L, Cazzaniga P, Rosaschino F

出版信息

Boll Ist Sieroter Milan. 1979 Mar 31;58(1):68-74.

PMID:552837
Abstract

Anti-whooping cough agglutinin titrations were performed in various groups of children by employing a special antigen and a microtechnique. Moderate agglutinating titers were detected in the first trimester of life and were interpreted as transmitted from the mother. Rare and moderate titers were observed in a group of children of school age, randomly selected and non institutionalized, while, on the contrary, an analogous institutionalized group showed more frequent and higher rate of antibodies. In clinically diagnosed whooping cough titers resulted high when the disease turned out to have set in more than three week earlier. Anti-whooping cough vaccination determined agglutinating titers mainly moderate and not long-lasting.

摘要

采用一种特殊抗原和微量技术,对不同组儿童进行了抗百日咳凝集素滴定。在生命的头三个月检测到中等凝集滴度,并被解释为来自母亲的传递。在一组随机选择的非机构化学龄儿童中观察到罕见和中等滴度,而相反,一组类似的机构化儿童显示出更频繁和更高的抗体率。在临床诊断为百日咳的情况下,当疾病在三周多以前就已发作时,滴度会很高。抗百日咳疫苗接种产生的凝集滴度主要为中等且持续时间不长。

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