大鼠肝脏对N-亚硝基-2-氧代丙基丙胺的代谢：氧化和还原产物的形成。
Metabolism of N-nitroso-2-oxopropylpropylamine by rat liver: formation of products resulting from both oxidation and reduction.
作者信息
Park K K, Archer M C
出版信息
Cancer Biochem Biophys. 1978;3(1):37-40.
PMID:552897
Abstract
Metabolism of N-nitroso-2-oxopropylpropylamine (NOPPA) with either a microsomal preparation or the soluble enzyme fraction from rat liver yielded N-nitroso-2-hydroxypropylpropylamine (NHPPA). We have also identified and quantified propionaldehyde, n-propanol and isopropanol following incubation of NOPPA with the microsomal fraction.
摘要
用大鼠肝脏微粒体制剂或可溶性酶组分对N-亚硝基-2-氧代丙基丙胺（NOPPA）进行代谢，生成了N-亚硝基-2-羟丙基丙胺（NHPPA）。在用微粒体组分孵育NOPPA后，我们还鉴定并定量了丙醛、正丙醇和异丙醇。
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