[5-溴-2'-脱氧尿苷诱导在经SV40转化的仓鼠细胞中先前未检测到的一种“泡沫状”病毒]
[Induction, by 5-bromo-2'-deoxyuridine, of a "foamy" virus previously undetected in hamster cells transformed by SV40].
作者信息
Rossignol J M, Kress M, de Vaux Saint Cyr C
出版信息
C R Acad Hebd Seances Acad Sci D. 1975 Oct 13;281(15):1145-8.
PMID:55314
Abstract
TSV5 clone 2 cells in normal conditions of culture contain only an expressed RNA virus (R-type virus). However, exposure of the cells to 5-bromo-2'-deoxyuridine with dexamethasone, induced synthesis of a syncitium-forming ("Foamy") virus. In other hamster cell lines, the same treatment fails to induce a "foamy" virus. The origin of this "foamy" virus is discussed.
摘要
在正常培养条件下，TSV5克隆2细胞仅含有一种表达的RNA病毒（R型病毒）。然而，将这些细胞暴露于5-溴-2'-脱氧尿苷和地塞米松中，会诱导合成一种形成多核巨细胞的（“泡沫状”）病毒。在其他仓鼠细胞系中，相同处理无法诱导出“泡沫状”病毒。本文讨论了这种“泡沫状”病毒的起源。
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