5-溴脱氧尿苷对转化小鼠克隆内源性C型病毒的超诱导作用
Superinduction of endogenous type C virus by 5-bromodeoxyuridine from transformed mouse clones.
作者信息
Lieber M M, Livingston D M, Todaro G J
出版信息
Science. 1973 Aug 3;181(4098):443-4. doi: 10.1126/science.181.4098.443.
PMID:4123998
Abstract
Certain transformed subclones of the mouse cell line BALB/3T3 release 5 to 15 times more type C virus per cell than the parent cell line after treatment with 5-bromodeoxyuridine. Virus release begins within 8 hours and exponentially increases for the first 24 to 48 hours. Superinducibility is associated with the transformed phenotype.
摘要
小鼠细胞系BALB/3T3的某些转化亚克隆在用5-溴脱氧尿苷处理后，每个细胞释放的C型病毒比亲代细胞系多5至15倍。病毒释放始于8小时内，并在最初的24至48小时呈指数增加。超诱导性与转化表型相关。
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