Palermo D, Milillo M A
Boll Soc Ital Biol Sper. 1979 Sep 30;55(18):1859-62.
The Authors carried out a research on the residues of Levamisole, a well known antihelmintic drug, in the muscles, livers, kidneys and blood from sheep treated with therapeutical doses. The results suggest that highest levamisole concentrations in the organs have been detected between the second and the third day (3.25 ppm in muscles; 1.40 ppm in livers; 0.22 ppm in kidneys). Remarkable residues have already been verified in blood during the first determination (4 h after the treatment) but these have been rapidly eliminated. Besides, a gradual diminution of the residues was observed until the seventh day from the treatment.
作者对治疗剂量的知名驱虫药左旋咪唑在绵羊肌肉、肝脏、肾脏和血液中的残留进行了研究。结果表明,在第二天至第三天期间,器官中检测到的左旋咪唑浓度最高(肌肉中为3.25 ppm;肝脏中为1.40 ppm;肾脏中为0.22 ppm)。在首次测定(治疗后4小时)时,血液中已检测到显著残留,但这些残留已迅速消除。此外,从治疗开始到第七天,观察到残留量逐渐减少。