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[丹曲林钠对豚鼠离体膀胱逼尿肌的作用]

[The effect of sodium dantrolene on the detrusor urinae muscle of the bladder isolated from guinea pigs].

作者信息

Lograno M D, Conte-Camerino D, De Filippis F

出版信息

Boll Soc Ital Biol Sper. 1979 Mar 15;55(5):484-8.

PMID:553606
Abstract

The effects of dantrolene sodium were evaluated in vitro using the guinea pig detrusor muscle preparation. Dantrolene reversibly decreased the strength of the responses of the detrusor to acetylcholine and histamine. The drug seems to depress the detrusor muscle of the bladder as it does others smooth muscles.

摘要

使用豚鼠逼尿肌制备物在体外评估了丹曲林钠的作用。丹曲林可逆地降低了逼尿肌对乙酰胆碱和组胺反应的强度。该药物似乎像对其他平滑肌一样抑制膀胱逼尿肌。

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