Ethacrynic acid effect on the composition of cochlear fluids.
作者信息
Cohn E S, Gordes E H, Brusilow S W
出版信息
Science. 1971 Mar 5;171(3974):910-1. doi: 10.1126/science.171.3974.910.
PMID:5541655
Abstract
Ethacrynic acid, when administered to six dogs, caused a fall in the concentration of potassium in endolymph from 145 to 21 milliequivalents per liter and a rise in the concentration of sodium from 5.9 to 146 milliequivalents per liter. The composition of perilymph is unaffected. Perilymph and endolymph are slightly hypertonic as compared to plasma.
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