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超感染噬菌体空壳对T4噬菌体增殖的抑制作用及噬菌体感染后耐受性的发展。

Inhibition of T4 bacteriophage multiplication by superinfecting ghosts and the development of tolerance after bacteriophage infection.

作者信息

Duckworth D H

出版信息

J Virol. 1971 Jan;7(1):8-14. doi: 10.1128/JVI.7.1.8-14.1971.

Abstract

Simultaneous addition of T4 phage and ghosts to host cells prevents infective center formation. Cells which have been infected with phage for less than 2 min are also inhibited by superinfecting ghosts. After this time, a chloramphenicol-inhibitable reaction occurs which causes the phage-infected cells to become increasingly tolerant of added ghosts.

摘要

同时向宿主细胞中添加T4噬菌体和噬菌体空壳可防止感染中心的形成。感染噬菌体不到2分钟的细胞也会受到超感染噬菌体空壳的抑制。在此之后,会发生一种氯霉素可抑制的反应,使被噬菌体感染的细胞对添加的噬菌体空壳越来越耐受。

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