Duckworth D H
J Virol. 1971 Nov;8(5):754-8. doi: 10.1128/JVI.8.5.754-758.1971.
The requirement for phage protein synthesis for the inhibition of host deoxyribonucleic acid synthesis has been investigated by using a phage mutant unable to catalyze the production of any phage deoxyribonucleic acid. It has been concluded that the major pathway whereby phage inhibit host syntheses requires protein synthesis. The inhibition of host syntheses by phage ghosts is not affected by inhibitors of protein synthesis.
利用一种无法催化任何噬菌体脱氧核糖核酸产生的噬菌体突变体,对噬菌体蛋白质合成抑制宿主脱氧核糖核酸合成的需求进行了研究。得出的结论是,噬菌体抑制宿主合成的主要途径需要蛋白质合成。噬菌体空壳对宿主合成的抑制不受蛋白质合成抑制剂的影响。