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[不同脂肪饮食对大鼠坐骨神经的结构改变(作者译)]

[Structural modifications of the sciatic nerve in rats on different fat diets (author's transl)].

作者信息

Gallai V, Binaglia L, Rossi A, Agostini L

出版信息

Riv Patol Nerv Ment. 1979 May-Jun;100(3):143-55.

PMID:554353
Abstract

The influence of dietary lipid components on fatty acids content of the sciatic nerve was studied in rats. Rats of both sexes were divided into three groups according to diet: 1. standard diet; 2. standard diet enriched with various seed oils; 3. colza oil-enriched diet. Six animals from each group (3 males and 3 females) were killed after 15, 30, 60 and 90 days, respectively, of controlled feedings. Their sciatic nerves were immediately removed and freeze-dried. Lipid extracts were prepared from each sample gas chromatography tests were made on the esterified fats. The results obtained show that there is a change in the fatty acids of the sciatic nerve lipids in rats on low fat diets, while the amount of phospholipids remains the same.

摘要

在大鼠中研究了膳食脂质成分对坐骨神经脂肪酸含量的影响。根据饮食将雌雄大鼠分为三组:1. 标准饮食;2. 添加各种植物油的标准饮食;3. 富含菜籽油的饮食。在分别进行15、30、60和90天的控制喂养后,每组处死6只动物(3只雄性和3只雌性)。立即取出它们的坐骨神经并冻干。从每个样品中制备脂质提取物,并对酯化脂肪进行气相色谱测试。所得结果表明,低脂饮食的大鼠坐骨神经脂质中的脂肪酸发生了变化,而磷脂的量保持不变。

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