Butler C, Kleinerman J
Br J Ind Med. 1971 Jan;28(1):67-71. doi: 10.1136/oem.28.1.67.
Butler, C. II, and Kleinerman, J. (1971). 28, 67-71. Paraquat in the rabbit. Forty rabbits received paraquat intraperitoneally in total dosages of from 2 to 100 mg/kg and in one to five separate administrations. Nine animals which received 25 mg/kg or more died within four days of administration, and the remainder were killed at intervals of up to one month. The delayed pulmonary changes produced in man and other species by paraquat were not found in any animal, despite the fact that most animals were made ill by the chemical. Atrophy of the thymus and minimal renal tubular and focal peritoneal changes were present in animals found dead or killed soon after administration, but it was difficult to explain the cause of death.
巴特勒,C. II,和克莱纳曼,J.(1971年)。28卷,67 - 71页。兔体内的百草枯。40只兔子接受了腹腔注射百草枯,总剂量为2至100毫克/千克,分1至5次给药。9只接受25毫克/千克或更高剂量的动物在给药后4天内死亡,其余动物在长达1个月的间隔时间内被处死。尽管大多数动物因这种化学物质而生病,但在任何动物中都未发现百草枯在人类和其他物种中产生的延迟性肺部变化。给药后不久死亡或被处死的动物出现胸腺萎缩以及轻微的肾小管和局灶性腹膜变化,但很难解释死亡原因。