Deze J, Völler G W
Acta Psychiatr Belg. 1979 Nov-Dec;79(6):704-11.
In an open study, 60 Parkinson patients with varying aetiology were submitted to a treatment with the long-acting antiparkinsonian drug dexetimide and L-Dopa. Rigor, tremor and akinesia were favourably influenced. An advantage over other antiparkinsonian agents is its long duration of action and the possibility of a simple dosage. Further investigations concerning its long-term effect and elucidation of its interactions with different drugs commonly administered in parkinsonian disorders seem desirable.
在一项开放性研究中,60名病因各异的帕金森病患者接受了长效抗帕金森病药物右旋醋甲唑胺和左旋多巴的治疗。僵直、震颤和运动不能均受到了积极影响。相较于其他抗帕金森病药物,其优势在于作用持续时间长且给药方式简单。关于其长期疗效以及与帕金森病常用的不同药物相互作用的进一步研究似乎很有必要。