Glomaud D, Meunier A, Girard P, Ngioing Tin L, Tonnelier M, Salamagne J C
Anesth Analg (Paris). 1979;36(11-12):551-6.
The hemodynamic consequences of the translumbar intra-aortic injection of 80 ml of contrast media were studied in 28 patients, in whom cardiac output was determined using thermodilution. These measurements revealed that the vasoplegia produced by the intra-aortic injection of contrast media is of smaller amplitude and longer duration than that evidenced during regional flow determinations. Moreover, the decrease in vascular peripheral resistances and the increase in cardiac output, accompanied by bradycardia, persist for several minutes. These phenomenons are related to an increase in ventricular filling, resulting from the expansion of the intravascular compartment secondary to plasma hyperosmolality.
对28例患者进行了研究，通过热稀释法测定心输出量，观察经腰段主动脉注入80ml造影剂后的血流动力学变化。这些测量结果显示，主动脉内注入造影剂所产生的血管麻痹，其幅度小于区域血流测定时所显示的幅度，而持续时间更长。此外，血管外周阻力降低、心输出量增加并伴有心动过缓，会持续几分钟。这些现象与心室充盈增加有关，心室充盈增加是由于血浆高渗导致血管内隔室扩张所致。
