半乳糖在仓鼠小肠中的转运：钠电化学势梯度的影响。
Galactose transport across the hamster small intestine: the effect of sodium electrochemical potential gradients.
作者信息
Smulders A P, Wright E M
出版信息
J Physiol. 1971 Jan;212(1):277-86. doi: 10.1113/jphysiol.1971.sp009322.
Abstract
- Measurements of galactose unidirectional fluxes across the isolated mucosa of the hamster small intestine were made under a variety of experimental conditions designed to investigate the interrelationships between galactose transport, the sodium ion and electrical potentials.2. Galactose transport was inhibited by lowering the sodium concentration in the mucosal and/or serosal solutions and by increasing the p.d. across the tissue. This inhibition of galactose transport was judged to be irreversible.3. Transport was unaffected by decreasing the p.d. across the tissue.4. These results are discussed in relation to the model proposed to explain galactose transport across the intestine.
摘要
在多种实验条件下，对经分离的仓鼠小肠黏膜的半乳糖单向通量进行了测量，这些实验条件旨在研究半乳糖转运、钠离子和电势之间的相互关系。
通过降低黏膜和/或浆膜溶液中的钠浓度以及增加组织两端的电位差，半乳糖转运受到抑制。这种对半乳糖转运的抑制被判定为不可逆。
降低组织两端的电位差对转运没有影响。
结合所提出的解释半乳糖跨肠转运的模型对这些结果进行了讨论。
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2
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J Gen Physiol. 1964 Jul;47(6):1043-59. doi: 10.1085/jgp.47.6.1043.
3
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J Physiol. 1964 Jun;171(2):316-38. doi: 10.1113/jphysiol.1964.sp007379.
4
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5
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Biochim Biophys Acta. 1962 May 7;59:78-93. doi: 10.1016/0006-3002(62)90699-6.
6
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7
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9
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