Gioanni J, Farges M F, Asin C, Lalanne C M
Bull Cancer. 1979;66(5):479-84.
The labelling index (LI) of 96 breast adenocarcinomas and of 43 upper respiratory and digestive tract cancers has been measured. For the two histological groups, the distribution of individual values is found to be log-normal, with a mean value depending on the tumour type. Our data have been compared with other authors results. The dispersion of individual values within a same histological type suggests that the LI is interesting as an individual value depending on the patient and his own cancer. For breast adenocarcinomas the LI values obtained have been separated in two groups depending upon the patient age, the age of 53 has been chosen to separate premenopausal from post-menopausal patients. A test of significance showed that the two corresponding log-normal distributions were different, even at the 0.01 level of significance, a mean LI value thus characterizing each distribution.
已对96例乳腺腺癌和43例上呼吸道及消化道癌症的标记指数(LI)进行了测量。对于这两个组织学组,发现个体值的分布呈对数正态分布,其平均值取决于肿瘤类型。我们的数据已与其他作者的结果进行了比较。同一组织学类型内个体值的离散性表明,LI作为取决于患者及其自身癌症的个体值很有意义。对于乳腺腺癌,根据患者年龄将获得的LI值分为两组,选择53岁作为区分绝经前和绝经后患者的年龄界限。显著性检验表明,即使在0.01的显著性水平下,两个相应的对数正态分布也是不同的,因此每个分布都有一个平均LI值作为特征。