Bolla M, Vrousos C, Horiot J C, Bordes M, Le Dorze C
Bull Cancer. 1979;66(5):525-9.
The authors analyse 123 cases of carcinoma of the uterine cervix treated by radiotherapy, with CEA radio-immuno-assay performed before treatment then each time patients are seen in follow-up. The CEA level is positive in 35 per cent of the cases with a mean value of 21 per cent for stage I, 36 per cent for stage II and 48 per cent for stage III. CEA level become negative at the end of the treatment (80%) or after (100%) when there is a complete disappearance of the tumour. The persistence of a positive level is well correlated with the abscence of sterilization, and reappearance of CEA evokes a recurrence. Preliminary results do not seem to show a prognosis value of pre-therapeutic level of CEA according to survival rate at 2 years.
作者分析了123例接受放射治疗的子宫颈癌病例，在治疗前及随访期间每次就诊时均进行癌胚抗原（CEA）放射免疫测定。35%的病例CEA水平呈阳性，其中I期病例的平均值为21%，II期为36%，III期为48%。当肿瘤完全消失时，80%的病例在治疗结束时CEA水平转为阴性，100%的病例在治疗后转为阴性。CEA水平持续呈阳性与未治愈密切相关，CEA再次出现提示复发。根据2年生存率，初步结果似乎未显示出治疗前CEA水平的预后价值。
