Braun P, Leyendecker G
Cancer Detect Prev. 1983;6(1-2):249-53.
Serum levels of carcinoembryonic antigen (CEA) were determined radioimmunologically before initiation of therapy in the serum of 142 patients suffering from carcinoma of the uterine cervix. The overall incidence of elevated CEA levels (above 12 ng/ml) was 39%. There was a positive correlation between the incidence of elevated CEA levels and the clinical stage of the disease. CEA levels before treatment had no prognostic value in patients matched for stage as far as median survival time was concerned. In contrast, CEA levels measured immediately after therapy in patients with initially elevated levels acquired prognostic significance. Thus, CEA measurements appear to be an additional tool in the follow-up of patients with cervical cancer.
采用放射免疫法测定了142例子宫颈癌患者治疗前血清中的癌胚抗原（CEA）水平。CEA水平升高（高于12 ng/ml）的总体发生率为39%。CEA水平升高的发生率与疾病的临床分期之间存在正相关。就中位生存时间而言，治疗前的CEA水平在分期匹配的患者中没有预后价值。相比之下，初始CEA水平升高的患者在治疗后立即检测的CEA水平具有预后意义。因此，CEA检测似乎是宫颈癌患者随访中的一项辅助手段。
