Radin E L
Bull Hosp Joint Dis. 1979;40:84-9.
Cartilage fibrillation does not necessarily progress. There appears to be different mechanical factors involved in the initiation and the progression of cartilage changes in osteoarthrosis. This means there is some rationale behind what we see clinically happening after successful osteotomy or other operations that lower the stress on degenerating joints, and it means that if we can do something about the level of stress and, therefore, the level of bone remodeling in patients with fibrillation, we may be able to keep that cartilage from further degenerating.
软骨纤维化不一定会进展。骨关节炎中软骨变化的起始和进展似乎涉及不同的力学因素。这意味着我们在成功进行截骨术或其他降低退变关节应力的手术后所观察到的临床现象背后存在一定的理论依据,也意味着如果我们能够对纤维化患者的应力水平以及骨重塑水平采取措施,我们或许能够防止软骨进一步退变。